In Episode 6 of the Lifespan podcast, Dr. David Sinclair and co-host Matthew LaPlante discuss cosmetic aging and how to improve skin, nails, and hair. They talk about why superficial aging occurs and how external signs of aging are often a reflection of biological age. The latest science behind various beautifying therapies is highlighted, including newer interventions like low-level laser therapy and platelet-rich plasma injections.
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To stay up to date with David's work to democratize biological age testing and insights, visit tallyhealth.com.
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Links
- Human faces and mortality predictions
- Biological age prediction in human skin
- Senescent cells and lifespan in mice
- Nail growth and aging
- Autophagy is a major regulator of aging
- Hyaluronan and cancer resistance
- Topical tretinoin and hair growth
- Dihydrotestosterone levels correlate with mortality
- Eunuchs are especially long-lived
- Human hair greying is linked to life stress
- Grey hair reversal in mice
Timestamps
00:00:00 Launching Episode Six: Combating Cosmetic Aging & Improving Skin, Nails & Hair
00:02:54 Estrogen, Progesterone, and Menopause
00:09:51 Thanking the Sponsors
00:12:57 The Pinch Test, Epidermal Thinning, and Foot Ulcers
00:18:29 Skin and Biological Aging
00:23:19 Cellular Senescence, Ultraviolet Light, and Skin Aging
00:28:15 Collagen, Keratin, and Skin Health
00:33:38 A Quick Aside about Nails
00:34:45 Autophagy and Retinoids
00:36:57 Resveratrol, NAD Boosters, and Hyaluronic Acid
00:41:44 Botox, Skin Peels, and Microneedling
00:43:28 No Duh Stuff: Sun Damage, Smoking, Alcohol, and Bad Food
00:45:42 Hair Loss and Hair Graying
00:49:45 Topical Treatments, Pills, and Dihydrotestosterone
00:55:19 Frickin Laser Beams: Low-level Laser Therapy
00:57:59 Platelet-rich Plasma (PRP) Injections
01:00:11 Hair Aging, Stress, and Gray Hair Reversal
01:06:11 Targeting Aging Upstream
01:07:37 Today’s Takeaways
01:09:25 Subscription and Support Options
